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10 Best L Methylfolate Supplement in 2022

Finding the best l methylfolate supplement is not an easy task. There are hundreds of similar products on the market which can cater to your needs, but only a few of them stand out from the rest. We have researched hundreds of customer reviews and feedback from all around the web before we made our top 10 list of l methylfolate supplement. We did the heavy lifting, and made the process easy for you. So without further ado, let’s get into the list.

10 Best L Methylfolate Supplement – Top Picks of 2022

Product 1
L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO, Gluten Free | Methyl Folate, 5-MTHF | by Opti-Folate
  • Gluten Free, Non-GMO; Free Of Wheat, Yeast, Milk, Lactose, Soy, Artificial Color, Artificial Flavor
  • Each L-Methylfolate (5-MTHF) capsule provides you with 15 mg of this bioavailable form of folic acid
  • Folate, also referred to as Folic Acid, is a fully active B complex vitamin
  • Our professional formula is backed by our commitment to purity and potency
  • Manufactured in a facility that is GMP certified
Product 2
Metabolic Maintenance L-Methylfolate 5mg - Active Folate (L-5-MTHF) + Glycine Supplement - B Vitamin for Mood, Nerve, Methylation + Cardiovascular Support (90 Capsules)
  • Get The Right Kind Of Folate - About half of the US population have a reduced ability to convert folic acid to 5-MTHF, the activated form of folate.*
  • Active & Bioavailable - Our L-Methylfolate is a more active, bioavailable form of folate. It is the only form of folate to cross the blood-brain-barrier.*
  • Cardiovascular, Nerve, & Mood Support - 5-MTHF is important for normal production of the neurotransmitters serotonin, norepinephrine, and dopamine. It also plays a part in the maintenance of cardiovascular and nerve health.*
  • Purity, Quality, Potency - No fillers, binders, preservatives, artificial colors or flavors. Vegetarian capsules. No gluten, egg, peanuts, tree nuts, or magnesium stearate. Supplements arrive in BPA-Free, recycled amber bottles that protect from light contamination.
  • Physician's Choice - The health care professional's choice for high-quality supplements since 1984. We base our products on the latest wellness research and clinical studies, and use third-party testing for all incoming, in-process, and finished product. Products you can trust, at an exceptional value.
Product 3
L Methylfolate 7.5 mg | 60 Capsules | Optimized and Activated | Non-GMO, Gluten Free | Methyl Folate, 5-MTHF | by Opti-Folate
  • Gluten Free, Non-GMO; Free Of Wheat, Yeast, Milk, Lactose, Soy, Artificial Color, Artificial Flavor
  • Each L-Methylfolate (5-MTHF) capsule provides you 7.5mg of this bioavailable form of folic acid
  • Folate, also referred to as Folic Acid, is a fully active B complex vitamin; 12,500mcg DFE of Folate
  • Our professional formula is backed by our commitment to purity and potency
  • Manufactured in a facility that is GMP certified
Product 4
MethylPro 15mg L-Methylfolate (30 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF Supplement for Mood, Homocysteine Methylation + Immune Support, Non-GMO + Gluten-Free with No Fillers
  • The Leader In Faster, Active Folate - Approximately half the US population may have difficulty converting folate into its active form. MethylPro is the leading nutraceutical line featuring l-methylfolate, the most advanced form for better results.*
  • Professional Strength - Many methylfolate products contain mcg or 1mg amounts. MethylPro offers a range of potent therapeutic doses. This 15 mg dose is our strongest, for a difference you can feel.*
  • Brain & Mood Support - Methylfolate is important for the production of neurotransmitters involved in concentration, sleep, energy, hormones and mood stability. This is the only form of folate to cross the blood-brain-barrier.*
  • Promotes Cardiovascular & Nerve Health - May help promote heart health & healthy peripheral nerve function by supporting already healthy homocysteine levels and nitric oxide production.*
  • No Fillers - MethylPro never uses fillers or excipients like bulking agents, glues, or binders. The only additional ingredient is the amino acid glycine. This product is free of soy, gluten, dairy, eggs, and nuts. Take only as directed under the supervision of a Physician.*
Product 5
MethylPro 15mg L-Methylfolate (90 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF Supplement for Mood, Homocysteine Methylation + Immune Support, Gluten-Free with No Fillers
  • The Leader In Faster, Active Folate - Approximately half the US population may have difficulty converting folate into its active form. MethylPro is the leading nutraceutical line featuring l-methylfolate, the most advanced form for better results.*
  • Professional Strength - Many methylfolate products contain mcg or 1mg amounts. MethylPro offers a range of potent therapeutic doses. This 15 mg dose is our strongest, for a difference you can feel.*
  • Brain & Mood Support - Methylfolate is important for the production of neurotransmitters involved in concentration, sleep, energy, hormones and mood stability. This is the only form of folate to cross the blood-brain-barrier.*
  • Promotes Cardiovascular & Nerve Health - May help promote heart health & healthy peripheral nerve function by supporting already healthy homocysteine levels and nitric oxide production.*
  • No Fillers - MethylPro never uses fillers or excipients like bulking agents, glues, or binders. The only additional ingredient is the amino acid glycine. This product is free of soy, gluten, dairy, eggs, and nuts. Take only as directed under the supervision of a Physician.*
Product 6
MD. Life L-Methylfolate 5 mg - Active Folate 5 Mthfr Support Supplement Professional Strength Methyl Folate - Essential Amino Acids & Brain Supplement- 90 Vegan Capsules
  • ACTIVE FOLATE THAT WORKS - This L methylfolate 5mg formula contains the ingredients necessary for your body to properly utilize folic acid, also known as a complex b9 vitamin. Unlike folic acid, the synthetic form of vitamin B9, methylfolate is the already converted form of folate people can easily use without the need of the MTHFR enzyme.*
  • SYNTHESIS AND REPAIR* - Methylfolate 5 mg, the most active form, is essential in the production and maintenance of new cells.*
  • THIRD PARTY TESTED FOR PURITY - All our brain supplements undergo extensive third -party testing to maintain the highest level of quality and purity in the manufacturing of our products. Having third party certification means these products comply with specific standards set for safety, quality and performance. These products are also made and packaged in the USA.
  • MOOD & BRAIN SUPPORT* – MD Life’s Methyl folate 5mg is a great choice for mood support. Sleep, concentration, energy, mood stability and hormone support are assisted by methylfolate.
Product 7
MD. Life L-Methylfolate 7.5 mg - Active Folate 5 Mthfr Support Supplement Professional Strength Methyl Folate - Essential Amino Acids & Brain Supplement- 90 Vegan Capsules
  • ACTIVE FOLATE THAT WORKS - This L methylfolate 7.5mg formula contains the ingredients necessary for your body to properly utilize folic acid, also known as a complex b9 vitamin. Unlike folic acid, the synthetic form of vitamin B9, methylfolate is the already converted form of folate people can easily use without the need of the MTHFR enzyme.*
  • SYNTHESIS AND REPAIR* - Methylfolate 7.5 mg, the most active form, is essential in the production and maintenance of new cells.*
  • THIRD PARTY TESTED FOR PURITY - All our brain supplements undergo extensive third -party testing to maintain the highest level of quality and purity in the manufacturing of our products. Having third party certification means these products comply with specific standards set for safety, quality and performance. These products are also made and packaged in the USA.
  • MOOD & BRAIN SUPPORT* – MD Life’s Methyl folate 7.5 mg is a great choice for mood support. Sleep, concentration, energy, mood stability and hormone support are assisted by methylfolate.
Product 8
Seeking Health Active B12 with L-5-MTHF, 60 Lozenges, Vitamin B12 Supplement, Supports Cellular Health, Cognitive Health, and Healthy Energy Levels, Vegan- and Vegetarian-Friendly B12 Vitamin, MTHFR
  • HEALTHY ENERGY LEVELS: Active B12 with L-5-MTHF by Seeking Health provides 1,360 mcg DFE (800 mcg) of pure non-racemic L-methylfolate in an easy-to-take lozenge, along with two active “coenzyme” forms of vitamin B12 to give you the energy you need.*
  • HEALTHY MOOD AND FOCUS: Experience a supported healthy mood, focus, energy, and clarity. Note: This is a situational supplement; only take it when you feel that you need it. Other than those times, don’t take it, or as directed by your healthcare professional.*
  • IDEAL FOR MTHFR GENE MUTATION: By taking this combination of methylated nutrients—methylfolate and methylcobalamin—in Active Vitamin B12 with L-5-MTHF, your methylation pathway is supported and your MTHFR gene mutation symptoms are supported.*
  • LOZENGE: This easy-to-take and great-tasting lozenge isn’t your typical daily supplement. You should take it on an as-needed basis, or as directed by your healthcare professional. When you have a slight brain fog or feel unfocused, or fatigued, start with a small portion.*
  • CONSISTENT QUALITY: At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing standards before any ingredient is allowed for use. We use only the highest-quality ingredients.
Product 9
Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets
  • BIOLOGICALLY ACTIVE FOLIC ACID — Our Optimized Folate formula promotes both cardiovascular and cognitive health with 1700 mcg of folate in the form of 5-MTHF (L-Methylfolate), the metabolically active form of folic acid.
  • WHY FOLATE? – Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with heart and brain health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Our formula provides 5-MTHF, so you don’t have to.
  • HEART & BRAIN-FRIENDLY NUTRIENT – Because folate helps inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular biomarker. Since healthy homocysteine levels have been associated with cognitive health, getting enough folate is especially crucial for individuals who want to maintain brain health.
  • INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free, and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.
  • LIVE YOUR HEALTHIEST LIFE - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. Our formulations are created using the ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.
Product 10
MethylPro 5mg L-Methylfolate (30 Capsules) - Professional Strength Active Methyl Folate, 5-MTHF Supplement for Mood, Homocysteine Methylation + Immune Support, Non-GMO + Gluten-Free with No Fillers
  • Are You Taking The Wrong Kind Of Folate? Approximately half the US population may have difficulty converting folate into its active form. MethylPro is the leading nutraceutical line featuring l-methylfolate, the most active, advanced form for better results.*
  • Purer, Faster, Stronger - Many methylfolate products contain mcg or 1mg amounts. MethylPro offers a range of therapeutic doses in their fastest, most potent form for a difference you can feel. No fillers or excipients like bulking agents.*
  • Brain & Mood Support - Methylfolate is important for the production of neurotransmitters involved in concentration, sleep, energy, hormones and mood stability. This is the only form of folate to cross the blood-brain-barrier.*
  • Promotes Cardiovascular & Nerve Health - May help promote heart health & healthy peripheral nerve function by supporting already healthy homocysteine levels and nitric oxide production.*
  • No Fillers - MethylPro never uses fillers or excipients like bulking agents, glues, or binders. The only additional ingredient is the amino acid glycine. This product is free of soy, gluten, dairy, eggs, and nuts. Take only as directed under the supervision of a Physician.*

Best L Methylfolate Supplement Buying Guide

Last year alone, we spent nearly three hundred billion dollars on more than two million products. That’s a ton of money being pumped into the marketplace. But how can you best guarantee you will get your hands on the best products? That’s why it’s important to have the proper advice before spending your money on l methylfolate supplement. That’s exactly what this guide is for. We’ve explained all the important aspects to look for and compiled all our findings into a comprehensive list, so you can easily access the information that you need.

  • Quality of the product: Quality is something that you should always be concerned about when purchasing the l methylfolate supplement. These days you can find so many products that are of bad quality that it is extremely difficult to tell the good ones from the bad ones.
  • Features of the product: Product features tell you if it will suit your needs and help you to make the right choice. However, features are not all the criteria for choosing a product. You also need to make sure that it works as described.
  • Price of the product: Price is another essential factor you should consider when you are shopping for l methylfolate supplement. Think about how much you need the product and compare it to the price you are willing to pay. Try to choose the item that you can afford and avoid paying overpriced products.
  • Existing customer reviews: When buying new l methylfolate supplement, you should always look for customer reviews. Because customer reviews tell you what other customers think about the product, they help you avoid making costly mistakes.
  • Online marketplace: What marketplace you’re buying the l methylfolate supplement from is going to make a difference. If you’re buying it off Amazon, make sure the seller has a good reputation with a comparatively lower Best Seller Rank (BSR) in the category where the product is listed. Please don’t buy it off a random person that only has a few reviews.

Final Words

So now you have all the information on the best l methylfolate supplement, and it’s your time to pick the suitable l methylfolate supplement for yourself. You can choose from our list without any hesitation. And don’t forget, you can’t go wrong with our recommendation.